April 24, 2023

Does CoQ10 cause blood clots?

Written by our expert

Ava

Avanthika Nityanand

M.Sc Human Genetics, B.Sc Plant Biology & Plant Biotechnology

Does CoQ10 cause blood clots?
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Individuals taking warfarin or other blood-thinning medications are often advised to stay off CoQ10. One reason for this is the chemical similarity between CoQ10 and vitamin K, which helps activate the main clotting protein.

However, no study confirms whether a CoQ10 can induce clot development in healthy individuals. 

One of the widespread concerns around the CoQ10 supplement is its contraindications with blood thinners, particularly Warfarin. CoQ10 is chemically similar to vitamin K.

Vitamin K helps activate prothrombin, the precursor to the main clotting enzyme- thrombin. CoQ10’s structural similarity to vitamin K has evoked questions about its possible interference with warfarin- a drug widely used to prevent blood clots. [ref]

CoQ10 essentially controls the energy supply to all the organs in the body, especially organs that require plenty of energy, such as muscles, the heart (a highly sophisticated muscle), the liver, lungs, and kidneys.

While CoQ10 is found naturally in your body, over time, the stock depletes as you age. Reduced levels of CoQ10 mean low energy levels. And since CoQ10 is also a highly potent antioxidant, low levels could also lead to more inflammation. And more inflammation means a higher risk for heart, liver, and kidney conditions. [ref]

Thanks to the immense progress in the healthcare industry, we can safely increase our CoQ10 body levels by taking supplements. Studies have shown that CoQ10 is a well-tolerated supplement with no severe side effects. Dosage varies from 100-300 mg per day as directed by your doctor.

  1. Jafari, Mehdi, et al. “Coenzyme Q10 in the treatment of heart failure: A systematic review of systematic reviews.” Indian Heart Journal vol. 70 Suppl 1, Suppl 1 (2018): S111-S117. doi:10.1016/j.ihj.2018.01.031
  2. https://www.nccih.nih.gov/health/coenzyme-q10
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