March 18, 2024

Is it Irritable Bowel Syndrome or Inflammatory Bowel Disease?

Written by our expert

Drneha

Dr. Neha Singh

Master's in Pathology (DNB) & MBBS

Is it Irritable Bowel Syndrome or Inflammatory Bowel Disease?
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When troubled by stomach pain, we often seek home remedies or possible solutions on the Internet.

However, the information provided by search engines can often be confusing and misleading.

Irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) are two distinct conditions. Both are chronic, meaning that the symptoms can flare up over time.

Both inflammatory bowel disease and irritable bowel syndrome can cause similar symptoms, including abdominal cramping and pains, diarrhea, and constipation.

Even though they have overlapping symptoms, the two have important differences.

Specialists diagnose these conditions based on these differences.

Infographic showing the symptoms of Ibd and Ibs.
Infographic showing common risk factors of irritable bowel syndrome Source

Here is a brief insight into understanding them better.

Irritable Bowel Syndrome (IBS)

Several risk factors may increase the likelihood of developing irritable bowel syndrome (IBS).

These can vary from person to person, and it's often a combination of factors that contribute to the development of the condition.

Some common risk factors for IBS include:

  • Gender: Women are more likely to develop IBS than men. Hormonal fluctuations, particularly changes during the menstrual cycle, may influence symptoms in some women.
  • Age: IBS can occur at any age but often begins in young adulthood. However, it can also develop later in life.
  • Family History: Having a family history of IBS or other gastrointestinal disorders may increase the risk of developing IBS. Genetics can play a role in predisposing individuals to the condition.
  • Stress: Stress doesn't directly cause IBS, but it can exacerbate symptoms or trigger flare-ups in people who already have the condition. High levels of anxiety or experiencing traumatic events may contribute to the development or worsening of symptoms.
  • Dietary Factors: Certain foods and beverages can trigger or worsen symptoms of IBS in susceptible individuals. Common triggers include dairy products, fatty foods, spicy foods, caffeine, alcohol, and carbonated beverages. Additionally, inadequate fiber intake or eating large meals can contribute to symptoms.
  • Gastrointestinal Infections: Previous episodes of acute gastrointestinal infections, such as gastroenteritis caused by bacteria or viruses, have been linked to developing IBS in some individuals. This is often referred to as post-infectious IBS (PI-IBS).
  • Abnormal Gut Microbiota: Imbalances in the gut microbiota (the community of microorganisms in the digestive tract) have been associated with IBS. Disruptions in the balance of beneficial and harmful bacteria in the gut may contribute to developing or exacerbating symptoms.
  • Mental Health Disorders: Conditions such as anxiety, depression, or other mental health disorders are commonly seen in individuals with IBS. There appears to be a bidirectional relationship between IBS and mental health, with each potentially influencing the other.
  • Medications: Certain medications, such as antibiotics, nonsteroidal anti-inflammatory drugs (NSAIDs), and some antidepressants, can affect gastrointestinal function and potentially contribute to symptoms of IBS in susceptible individuals.
Infographic showing common risk factors of irritable bowel syndrome
Infographic showing common risk factors of irritable bowel syndrome Source
  • Cause: The exact cause of IBS is unknown, but it's believed to involve a combination of factors, including abnormal muscle contractions in the intestines, heightened sensitivity to food and stress, inflammation in the intestines, and changes in gut bacteria.
  • Symptoms: Common symptoms of IBS include abdominal pain or cramping, bloating, gas, diarrhea, constipation, or alternating diarrhea and constipation. Symptoms can vary in severity and may come and go over time.
  • Diagnosis: IBS is typically diagnosed based on symptoms and the exclusion of other conditions through medical history, physical examination, and possibly tests such as blood tests, stool tests, or imaging studies.
  • Treatment: Treatment for IBS often involves dietary changes, stress management techniques, lifestyle modifications, and medications to alleviate symptoms, such as antispasmodics, laxatives, or antidepressants.

Inflammatory Bowel Disease (IBD)

Inflammatory bowel disease (IBD), which includes conditions like Crohn's disease and ulcerative colitis, has several risk factors that can contribute to its development.

While the exact cause of IBD is not fully understood, these risk factors may increase the likelihood of developing the condition:

  • Genetics: A family history of IBD is one of the strongest risk factors. Individuals with a close relative (parent, sibling, or child) with IBD are at a higher risk of developing the condition themselves. Certain genetic variations, particularly those related to the immune system, can predispose individuals to IBD.
  • Immune System Dysfunction: IBD is characterized by an abnormal immune response in the gastrointestinal tract. Dysfunction of the immune system, where it mistakenly attacks healthy cells in the digestive tract, is thought to play a significant role in the development of IBD.
  • Environmental Factors: Environmental factors may trigger or exacerbate IBD in genetically susceptible individuals. Smoking, diet (including high-fat or processed foods), antibiotic use, pollution, and certain infections have been implicated as potential environmental triggers.
  • Smoking: Smoking is a significant risk factor for Crohn's disease, particularly for individuals who have a family history of the condition. In contrast, smoking may have a protective effect against ulcerative colitis, with fewer cases observed among smokers compared to non-smokers.
  • Age: Although IBD can occur at any age, it most commonly develops in adolescents and young adults. However, it can also develop later in life.
  • Ethnicity and Geography: Certain ethnic groups, such as Ashkenazi Jews, have a higher risk of developing IBD compared to others. Additionally, the incidence of IBD varies geographically, with higher rates observed in developed countries and urban areas.
  • Dietary Factors: While the role of diet in IBD development is complex and not fully understood, some dietary factors may influence the risk of developing or exacerbating the condition. High intake of processed foods, refined sugars, and certain fats may contribute to inflammation in the gut.
  • Antibiotic Use: Some studies suggest that antibiotic use, particularly during early childhood, may be associated with an increased risk of developing IBD. Antibiotics can alter the gut microbiota, potentially disrupting the balance of beneficial and harmful bacteria in the intestines.
  • Stress and Mental Health: While stress does not directly cause IBD, it can exacerbate symptoms in individuals who already have the condition. Additionally, there may be a bidirectional relationship between IBD and mental health disorders such as anxiety and depression, with each potentially influencing the other.
  • Types: IBD primarily includes two conditions: Crohn's disease and ulcerative colitis. Both are characterized by chronic inflammation of the digestive tract, but they differ in the location and nature of the inflammation.
Infographic demonstrating the progression of inflammatory bowel disease
Infographic demonstrating the progression of inflammatory bowel disease Source
  • Cause: The exact cause of IBD is unknown, but it is believed to involve an abnormal immune response to environmental triggers in genetically susceptible individuals. Genetics, immune system dysfunction, and environmental factors may play a role.
  • Symptoms: Symptoms of IBD can include abdominal pain, diarrhea (which may be bloody), rectal bleeding, weight loss, fatigue, and fever. The symptoms can range from mild to severe and may fluctuate over time.
  • Diagnosis: IBD diagnosis involves a combination of medical history, physical examination, imaging studies (such as colonoscopy or endoscopy), and laboratory tests (such as blood and stool tests) to assess inflammation and rule out other conditions.
  • Treatment: Treatment for IBD aims to reduce inflammation, control symptoms, and prevent complications. This may include medications such as anti-inflammatory drugs, immunosuppressants, biologic therapies, dietary changes, and, in some cases, surgery to remove affected portions of the digestive tract.
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